DISEASES

Disease-gene associations mined from literature

Literature on FHOD1

FHOD1 [ENSP00000258201]

FH1/FH2 domain-containing protein 1; Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing.

Synonyms:  FHOD1,  FHOD1p,  hFHOD1,  H3BVE7,  J3KT53 ...

Linkouts:  STRING  Pharos  UniProt  OMIM