DISEASES

Disease-gene associations mined from literature

Literature on NEK11

NEK11 [ENSP00000372857]

Serine/threonine-protein kinase Nek11; Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation. ; Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

Synonyms:  NEK11,  NEK11p,  hNEK11,  A0A075B7B3,  D6RGV6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM