DISEASES

Disease-gene associations mined from literature

Literature on PPM1E

PPM1E [ENSP00000312411]

Protein phosphatase 1E; Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2 (By similarity). Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Dephosphorylates PRKAA2 (By similarity); Belongs to the PP2C family.

Synonyms:  PPM1E,  PPM1Ep,  hPPM1E,  Q8WY54,  Q8WY54p ...

Linkouts:  STRING  Pharos  UniProt