DISEASES

Disease-gene associations mined from literature

Literature associating NEK3 and fiedler's myocarditis

NEK3 [ENSP00000484443]

Serine/threonine-protein kinase Nek3; Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contributes to prolactin-mediated phosphorylation of PXN and VAV2. Implicated in prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2.

Synonyms:  NEK3,  NEK3p,  hNEK3,  A0A087WY58,  A0A087X030 ...

Linkouts:  STRING  Pharos  UniProt