DISEASES

Disease-gene associations mined from literature

Literature associating FURIN and avian influenza

FURIN [ENSP00000483552]

Furin; Ubiquitous endoprotease within constitutive secretory pathways capable of cleavage at the RX(K/R)R consensus motif (PubMed:11799113, PubMed:1629222, PubMed:1713771, PubMed:2251280, PubMed:24666235, PubMed:25974265, PubMed:7592877, PubMed:7690548, PubMed:9130696). Mediates processing of TGFB1, an essential step in TGF-beta-1 activation . ECO:0000269|PubMed:1629222, ECO:0000269|PubMed:1713771, ECO:0000269|PubMed:2251280, ECO:0000269|PubMed:24666235, ECO:0000269|PubMed:25974265, ECO:0000269|PubMed:7592877, ECO:0000269|PubMed:7690548, ECO:0000269|PubMed:7737999, (Microbial infection) Required for H7N1 and H5N1 influenza virus infection probably by cleaving hemagglutinin.

Synonyms:  FURIN,  A0A024RC70,  A0A1W2PPZ9,  H0YKB2,  H0YLH7 ...

Linkouts:  STRING  Pharos  UniProt