DISEASES

Disease-gene associations mined from literature

Literature associating TCTN3 and short-rib thoracic dysplasia 6 with or without polydactyly

TCTN3 [ENSP00000483364]

Tectonic-3; Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). May be involved in apoptosis regulation. Necessary for signal transduction through the sonic hedgehog (Shh) signaling pathway.

Synonyms:  TCTN3,  TCTN3p,  hTCTN3,  A0A0C4DFN5,  Q6NUS6 ...

Linkouts:  STRING  Pharos  UniProt