Literature associating TMEM106A and benign breast phyllodes tumor
TMEM106A [ENSP00000483246]
Transmembrane protein 106A; Activates macrophages and polarizes them into M1-like macrophages through the activation of the MAPK and NF-kappaB signaling pathway. Upon activation, upregulates the expression of CD80, CD86, CD69 and MHC II on macrophages, and induces the release of pro- inflammatory cytokines such as TNF, IL1B, IL6, CCL2 and nitric oxide (By similarity). May play a role in inhibition of proliferation and migration . ; Belongs to the TMEM106 family.
Synonyms: TMEM106A, B7Z779, K7ERE2, Q96A25, B7Z779p ...