DISEASES

Disease-gene associations mined from literature

Literature associating DHRS11 and epithelial malignant thymoma

DHRS11 [ENSP00000482704]

Dehydrogenase/reductase SDR family member 11; Catalyzes the conversion of the 17-keto group of estrone, 4- and 5-androstenes and 5-alpha-androstanes into their 17-beta- hydroxyl metabolites and the conversion of the 3-keto group of 3-, 3,17- and 3,20- diketosteroids into their 3-hydroxyl metabolites. Exhibits reductive 3-beta-hydroxysteroid dehydrogenase activity toward 5-beta-androstanes, 5-beta-pregnanes, 4-pregnenes and bile acids. May also reduce endogenous and exogenous alpha-dicarbonyl compounds and xenobiotic alicyclic ketones.

Synonyms:  DHRS11,  DHRS11p,  hDHRS11,  A0A024R0T1,  A0A087WYV4 ...

Linkouts:  STRING  Pharos  UniProt