DISEASES

Disease-gene associations mined from literature

Literature associating MAP3K14 and trichohepatoenteric syndrome

MAP3K14 [ENSP00000482657]

Mitogen-activated protein kinase kinase kinase 14; Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P100, which leads to activation of NF-kappa-B via the non- canonical pathway. Could act in a receptor-selective manner.

Synonyms:  MAP3K14,  MAP3K14p,  hMAP3K14,  A0A087WXF1,  Q99558 ...

Linkouts:  STRING  Pharos  UniProt