Literature associating TYW1B and Sorsby's fundus dystrophy
TYW1B [ENSP00000482502]
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B; Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis (By similarity).
Synonyms: TYW1B, TYW1Bp, hTYW1B, A0A087WWV6, A0A087X1V1 ...