DISEASES

Disease-gene associations mined from literature

Literature associating PLCG2 and B cell deficiency

PLCG2 [ENSP00000482457]

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.

Synonyms:  PLCG2,  PLCG2p,  hPLCG2,  A0A0A0MRF9,  H3BMT7 ...

Linkouts:  STRING  Pharos  UniProt