DISEASES

Disease-gene associations mined from literature

Literature associating PIGW and iridogoniodysgenesis syndrome

PIGW [ENSP00000482202]

Phosphatidylinositol-glycan biosynthesis class W protein; Required for the transport of GPI-anchored proteins to the plasma membrane . Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins (By similarity). ; Belongs to the PIGW family.

Synonyms:  PIGW,  A0A087WWS9,  Q7Z7B1,  Q7Z7B1p,  hQ7Z7B1 ...

Linkouts:  STRING  Pharos  UniProt