DISEASES

Disease-gene associations mined from literature

Literature associating KCNN3 and Hirschsprung's disease

KCNN3 [ENSP00000481848]

Small conductance calcium-activated potassium channel protein 3; Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin; Belongs to the potassium channel KCNN family. KCa2.3/KCNN3 subfamily.

Synonyms:  KCNN3,  KCNN3p,  hKCNN3,  A0A087WYJ0,  A0A0A0MQW9 ...

Linkouts:  STRING  Pharos  UniProt