Literature associating H2BS1 and autosomal recessive Alport syndrome
H2BS1 [ENSP00000481622]
Histone H2B type F-S; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms: H2BS1, H2BS1p, hH2BS1, H2BFS, P57053 ...