DISEASES

Disease-gene associations mined from literature

Literature associating CBY1 and short chain acyl-CoA dehydrogenase deficiency

CBY1 [ENSP00000478962]

Protein chibby homolog 1; Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta- catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation. ; Belongs to the chibby family.

Synonyms:  CBY1,  CBY1p,  hCBY1,  A0A024R1L9,  A0A087WUW0 ...

Linkouts:  STRING  Pharos  UniProt