DISEASES

Disease-gene associations mined from literature

Literature associating SEC14L2 and atrophic rhinitis

SEC14L2 [ENSP00000478755]

SEC14-like protein 2; Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha- tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell.

Synonyms:  SEC14L2,  SEC14L2p,  hSEC14L2,  A0A024R1I5,  B3KRD8 ...

Linkouts:  STRING  Pharos  UniProt