DISEASES

Disease-gene associations mined from literature

Literature associating ABCB1 and germ cell cancer

ABCB1 [ENSP00000478255]

ATP-dependent translocase ABCB1; Translocates drugs and phospholipids across the membrane . Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins . Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells .

Synonyms:  ABCB1,  ABCB1p,  hABCB1,  A4D1D2,  E7EWT8 ...

Linkouts:  STRING  Pharos  UniProt