DISEASES

Disease-gene associations mined from literature

Literature associating STAG3 and premature menopause

STAG3 [ENSP00000477973]

Cohesin subunit SA-3; Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.

Synonyms:  STAG3,  STAG3p,  hSTAG3,  C9J3T3,  C9JTG4 ...

Linkouts:  STRING  Pharos  UniProt