Literature associating H4C7 and congenital bile acid synthesis defect
H4C7 [ENSP00000477870]
Histone H4-like protein type G; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity).
Synonyms: H4C7, H4C7p, hH4C7, HIST1H4G, Q99525 ...