DISEASES

Disease-gene associations mined from literature

Literature associating SNRNP70 and Libman-Sacks endocarditis

SNRNP70 [ENSP00000472998]

U1 small nuclear ribonucleoprotein 70 kDa; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome . SNRNP70 binds to the loop I region of U1-snRNA (PubMed:2467746, PubMed:19325628, PubMed:25555158). [Isoform 4]: Truncated isoforms that lack the RRM domain cannot bind U1-snRNA.

Synonyms:  SNRNP70,  SNRNP70p,  hSNRNP70,  A0A024QZD5,  M0QX04 ...

Linkouts:  STRING  Pharos  UniProt  OMIM