DISEASES

Disease-gene associations mined from literature

Literature associating TLE2 and anterior cranial fossa meningioma

TLE2 [ENSP00000466542]

Transducin-like enhancer protein 2; Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full- length TLE family members may be modulated by association with dominant-negative AES (By similarity); Belongs to the WD repeat Groucho/TLE family.

Synonyms:  TLE2,  TLE2p,  hTLE2,  K7EJR7,  K7EK93 ...

Linkouts:  STRING  Pharos  UniProt