DISEASES

Disease-gene associations mined from literature

Literature associating FAAP24 and lymphoproliferative syndrome 2

FAAP24 [ENSP00000466121]

Fanconi anemia core complex-associated protein 24; Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA.

Synonyms:  FAAP24,  FAAP24p,  hFAAP24,  A0A0S2Z5V6,  C19orf40 ...

Linkouts:  STRING  Pharos  UniProt