Literature associating MPPE1 and agnathia-otocephaly complex
MPPE1 [ENSP00000465894]
Metallophosphoesterase 1; Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI- anchor proteins; Belongs to the metallophosphoesterase superfamily. MPPE1 family.
Synonyms: MPPE1, MPPE1p, hMPPE1, A0A075B777, A0A0A0MR93 ...