Literature associating RNF43 and pancreatoblastoma
RNF43 [ENSP00000463069]
E3 ubiquitin-protein ligase RNF43; E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway . Along with RSPO2 and ZNRF3, constitutes a master switch that governs limb specification (By similarity). ECO:0000269|PubMed:18313049, ECO:0000269|PubMed:22575959,
Synonyms: RNF43, RNF43p, hRNF43, J3KSE3, Q68DV7 ...