DISEASES

Disease-gene associations mined from literature

Literature associating GDF2 and telangiectasis

GDF2 [ENSP00000463051]

Growth/differentiation factor 2; Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG. ECO:0000269|PubMed:21710321, ECO:0000269|PubMed:22799562,

Synonyms:  GDF2,  GDF2p,  hGDF2,  Q9UK05,  Q9UK05p ...

Linkouts:  STRING  Pharos  UniProt