DISEASES

Disease-gene associations mined from literature

Literature associating ADCYAP1 and chronic fatigue syndrome

ADCYAP1 [ENSP00000462647]

Pituitary adenylate cyclase-activating polypeptide 27; Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion (By similarity). Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells (By similarity). ECO:0000250|UniProtKB:P13589, ECO:0000269|PubMed:11175907,; Belongs to the glucagon family.

Synonyms:  ADCYAP1,  ADCYAP1p,  hADCYAP1,  P18509,  P18509p ...

Linkouts:  STRING  Pharos  UniProt