DISEASES

Disease-gene associations mined from literature

Literature associating DUS2 and autosomal recessive chronic granulomatous disease cytochrome b-positive type I

DUS2 [ENSP00000455229]

tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; Dihydrouridine synthase. Catalyzes the NADPH-dependent synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs . Negatively regulates the activation of EIF2AK2/PKR .

Synonyms:  DUS2,  DUS2p,  hDUS2,  A0A024R6Z7,  DUS2L ...

Linkouts:  STRING  Pharos  UniProt