DISEASES

Disease-gene associations mined from literature

Literature associating ITGAX and monocyte, dendritic cell, and NK cell deficiency

ITGAX [ENSP00000454623]

Integrin alpha-X; Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.

Synonyms:  ITGAX,  A0A087X131,  H3BN02,  P20702,  H3BN02p ...

Linkouts:  STRING  Pharos  UniProt