DISEASES

Disease-gene associations mined from literature

Literature associating B2M and MALT lymphoma

B2M [ENSP00000452780]

Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation; Belongs to the beta-2-microglobulin family.

Synonyms:  B2M,  B2Mp,  hB2M,  F5H6I0,  J3KNU0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM