DISEASES

Disease-gene associations mined from literature

Literature associating NDRG2 and Charcot-Marie-Tooth disease type 4D

NDRG2 [ENSP00000451712]

Protein NDRG2; Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation.

Synonyms:  NDRG2,  NDRG2p,  hNDRG2,  A0A0A0MS87,  A0A0U1RR50 ...

Linkouts:  STRING  Pharos  UniProt