DISEASES

Disease-gene associations mined from literature

Literature associating ZBTB1 and Parkinson's disease 7

ZBTB1 [ENSP00000451000]

Zinc finger and BTB domain-containing protein 1; Acts as a transcriptional repressor . Represses cAMP-responsive element (CRE)-mediated transcriptional activation . In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis . Plays a key role in the transcriptional regulation of T lymphocyte development (By similarity). ECO:0000269|PubMed:20797634, ECO:0000269|PubMed:21706167,

Synonyms:  ZBTB1,  ZBTB1p,  hZBTB1,  G3V2I8,  G3V3N0 ...

Linkouts:  STRING  Pharos  UniProt