DISEASES

Disease-gene associations mined from literature

Literature associating SLIRP and French Canadian Leigh disease

SLIRP [ENSP00000450909]

SRA stem-loop-interacting RNA-binding protein, mitochondrial; RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation.

Synonyms:  SLIRP,  A0A087WUN7,  G3V2S9,  G3V4X6,  H0YJ07 ...

Linkouts:  STRING  Pharos  UniProt