DISEASES

Disease-gene associations mined from literature

Literature associating IL11RA and cartilage-hair hypoplasia

IL11RA [ENSP00000450565]

Interleukin-11 receptor subunit alpha; Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.

Synonyms:  IL11RA,  IL11RAp,  hIL11RA,  G3V2A5,  G3V2G0 ...

Linkouts:  STRING  Pharos  UniProt