DISEASES

Disease-gene associations mined from literature

Literature associating SPIC and Cauda equina syndrome

SPIC [ENSP00000448580]

Transcription factor Spi-C; Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression (By similarity); Belongs to the ETS family.

Synonyms:  SPIC,  Q8N5J4,  Q8N5J4p,  hQ8N5J4,  121599 ...

Linkouts:  STRING  Pharos  UniProt