DISEASES

Disease-gene associations mined from literature

Literature associating PCSK5 and avian influenza

PCSK5 [ENSP00000446280]

Proprotein convertase subtilisin/kexin type 5; Serine endoprotease that processes various proproteins by cleavage at paired basic amino acids, recognizing the RXXX[KR]R consensus motif. Likely functions in the constitutive and regulated secretory pathways. Plays an essential role in pregnancy establishment by proteolytic activation of a number of important factors such as BMP2, CALD1 and alpha-integrins; Belongs to the peptidase S8 family.

Synonyms:  PCSK5,  PCSK5p,  hPCSK5,  B1AMG5,  B1AMG8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM