Literature associating PRAME and acute leukemia
PRAME [ENSP00000445675]
Melanoma antigen preferentially expressed in tumors; Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.
Synonyms: PRAME, A0A024R1E6, B5MCY4, B5MD04, E7EMH2 ...