DISEASES

Disease-gene associations mined from literature

Literature associating SCO2 and complement component 2 deficiency

SCO2 [ENSP00000444433]

Protein SCO2 homolog, mitochondrial; Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2 . Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2 .

Synonyms:  SCO2,  SCO2p,  hSCO2,  A0A1W2PQK0,  O43819 ...

Linkouts:  STRING  Pharos  UniProt