Literature associating AUNIP and breast apocrine carcinoma
AUNIP [ENSP00000443647]
Aurora kinase A and ninein-interacting protein; DNA-binding protein that accumulates at DNA double-strand breaks (DSBs) following DNA damage and promotes DNA resection and homologous recombination . Serves as a sensor of DNA damage: binds DNA with a strong preference for DNA substrates that mimic structures generated at stalled replication forks, and anchors RBBP8/CtIP to DSB sites to promote DNA end resection and ensuing homologous recombination repair . Inhibits non- homologous end joining (NHEJ) . Required for the dynamic movement of AURKA at the centrosomes and spindle apparatus during the cell cycle ; Belongs to the AUNIP family.
Synonyms: AUNIP, Q9H7T9, Q9H7T9p, hQ9H7T9, 79000 ...