DISEASES

Disease-gene associations mined from literature

Literature associating NR4A1 and salivary gland cancer

NR4A1 [ENSP00000440864]

Nuclear receptor subfamily 4 group A member 1; Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. Plays a role in the vascular response to injury (By similarity). ECO:0000250|UniProtKB:P12813, ECO:0000269|PubMed:15466594,

Synonyms:  NR4A1,  NR4A1p,  hNR4A1,  A0A024R126,  F5GXF0 ...

Linkouts:  STRING  Pharos  UniProt