DISEASES

Disease-gene associations mined from literature

Literature associating ZCCHC8 and gliofibroma

ZCCHC8 [ENSP00000438993]

Zinc finger CCHC domain-containing protein 8; Scaffolding subunit of the trimeric nuclear exosome targeting (NEXT) complex. NEXT functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation. NEXT is involved in surveillance and turnover of aberrant transcripts and non-coding RNAs . May be involved in pre-mRNA splicing (Probable); Belongs to the ZCCHC8 family.

Synonyms:  ZCCHC8,  ZCCHC8p,  hZCCHC8,  F5GX80,  F5GYI9 ...

Linkouts:  STRING  Pharos  UniProt