DISEASES

Disease-gene associations mined from literature

Literature associating KIF1A and hereditary sensory neuropathy

KIF1A [ENSP00000438388]

Kinesin-like protein KIF1A; Motor for anterograde axonal transport of synaptic vesicle precursors. Also required for neuronal dense core vesicles (DCVs) transport to the dendritic spines and axons. The interaction calcium- dependent with CALM1 increases vesicle motility and interaction with the scaffolding proteins PPFIA2 and TANC2 recruits DCVs to synaptic sites; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Unc-104 subfamily.

Synonyms:  KIF1A,  KIF1Ap,  hKIF1A,  A0A3B3IT28,  A0A3B3ITE5 ...

Linkouts:  STRING  Pharos  UniProt