DISEASES

Disease-gene associations mined from literature

Literature associating CACNG5 and spinal cord glioma

CACNG5 [ENSP00000436836]

Voltage-dependent calcium channel gamma-5 subunit; Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating properties by accelerating their rates of activation, deactivation and desensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2. Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity).

Synonyms:  CACNG5,  CACNG5p,  hCACNG5,  Q9UF02,  Q9UF02p ...

Linkouts:  STRING  Pharos  UniProt