DISEASES

Disease-gene associations mined from literature

Literature associating AGBL2 and tenosynovitis

AGBL2 [ENSP00000435582]

Cytosolic carboxypeptidase 2; Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin.

Synonyms:  AGBL2,  AGBL2p,  hAGBL2,  A0A140VKH9,  E9PI49 ...

Linkouts:  STRING  Pharos  UniProt