Literature associating PROM1 and cone-rod dystrophy
PROM1 [ENSP00000426809]
Prominin-1; May play a role in cell differentiation, proliferation and apoptosis . Binds cholesterol in cholesterol- containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner .
Synonyms: PROM1, PROM1p, hPROM1, A0A0A0N0M1, CD133 ...