DISEASES

Disease-gene associations mined from literature

Literature associating AADAT and detrusor sphincter dyssynergia

AADAT [ENSP00000423190]

Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro). ; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

Synonyms:  AADAT,  D6RC56,  D6REB9,  D6RFY7,  Q4W5N8 ...

Linkouts:  STRING  Pharos  UniProt