DISEASES

Disease-gene associations mined from literature

Literature associating AWAT2 and dentin caries

AWAT2 [ENSP00000421172]

Acyl-CoA wax alcohol acyltransferase 2; Acyltransferase that catalyzes the formation of ester bonds between fatty alcohols and fatty acyl-CoAs to form wax monoesters . Shows a preference for medium chain acyl-CoAs from C12 to C16 in length and fatty alcohols shorter than C20, as the acyl donors and acceptors, respectively . Also possesses acyl- CoA retinol acyltransferase (ARAT) activity that catalyzes 11-cis- specific retinyl ester synthesis . Shows higher catalytic efficiency toward 11-cis-retinol versus 9-cis- retinol, 13-cis-retinol, and all-trans-retinol substrates . ECO:0000269|PubMed:15671038, ECO:0000269|PubMed:16106050,

Synonyms:  AWAT2,  AWAT2p,  hAWAT2,  H0YAL0,  Q6E213 ...

Linkouts:  STRING  Pharos  UniProt