Literature associating PHC3 and primary hyperoxaluria type 3
PHC3 [ENSP00000420294]
Polyhomeotic-like protein 3; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Synonyms: PHC3, PHC3p, hPHC3, B4DTC4, C9J6H0 ...