DISEASES

Disease-gene associations mined from literature

Literature associating SUCLG2 and subacute bacterial endocarditis

SUCLG2 [ENSP00000419325]

Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

Synonyms:  SUCLG2,  SUCLG2p,  hSUCLG2,  A0A024R325,  E9PDQ8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM