DISEASES

Disease-gene associations mined from literature

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Literature associating PRKRIP1 and Noonan syndrome 6

PRKRIP1 [ENSP00000419270]

PRKR-interacting protein 1; Required for pre-mRNA splicing as component of the spliceosome . Binds double-stranded RNA. Inhibits EIF2AK2 kinase activity (By similarity).

Synonyms:  PRKRIP1,  PRKRIP1p,  hPRKRIP1,  A0A024QYV5,  E9PC43 ...

Linkouts:  STRING  Pharos  UniProt

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.