DISEASES

Disease-gene associations mined from literature

Literature associating CACNA2D2 and Brugada syndrome 4

CACNA2D2 [ENSP00000418081]

Voltage-dependent calcium channel subunit alpha-2/delta-2; The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Acts as a regulatory subunit for P/Q- type calcium channel (CACNA1A), N-type (CACNA1B), L-type (CACNA1C OR CACNA1D) and possibly T-type (CACNA1G) (PubMed:15111129, PubMed:23339110). Overexpression induces apoptosis.

Synonyms:  CACNA2D2,  C9JE82,  C9JVC9,  Q9NY47,  C9JE82p ...

Linkouts:  STRING  Pharos  UniProt  OMIM